La recherche au service de la performance en Santé
U.INSERM 1290 - La recherche au service de la performance en Santé
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Université Claude Bernard Lyon 1
U.INSERM 1290 - La recherche au service de la performance en Santé

Actualités du laboratoire Hesper

External validation of the Hospital Frailty Risk Score in France.

Gilbert T, Cordier Q, Polazzi S, Bonnefoy M, Keeble E, Street A, Conroy S, Duclos A.

External validation of the Hospital Frailty Risk Score in France.

Age Ageing. 2021 Jun 26:afab126. doi: 10.1093/ageing/afab126. Online ahead of print.

PMID: 34185827

Background: The Hospital Frailty Risk Score (HFRS) has made it possible internationally to identify subgroups of patients with characteristics of frailty from routinely collected hospital data.

Objective: To externally validate the HFRS in France.

Design: A retrospective analysis of the French medical information database.

Setting: 743 hospitals in Metropolitan France.

Subjects: All patients aged 75 years or older hospitalised as an emergency in 2017 (n = 1,042,234).

https://pubmed.ncbi.nlm.nih.gov/34185827/

TEOS: A framework for constructing operational definitions of medication adherence based on Timelines-Events-Objectives-Sources.

Dima AL, Allemann SS, Dunbar-Jacob J, Hughes DA, Vrijens B, Wilson IB.

TEOS: A framework for constructing operational definitions of medication adherence based on Timelines-Events-Objectives-Sources.

Br J Clin Pharmacol. 2021 Jun;87(6):2521-2533. doi: 10.1111/bcp.14659. Epub 2020 Dec 30.

PMID: 33220097

Aims :                                                                                                                                                                                                                                                                            Managing adherence to medications is a priority for health systems worldwide. Adherence research is accumulating, yet the quality of the evidence is reduced by various methodological limitations. In particular, the heterogeneity and low accuracy of adherence measures have been highlighted in many literature reviews. Recent consensus-based guidelines advise on best practices in defining adherence (ABC) and reporting of empirical studies (EMERGE). While these guidelines highlight the importance of operational definitions in adherence measurement, such definitions are rarely included in study reports. To support researchers in their measurement decisions, we developed a structured approach to formulate operational definitions of adherence.

https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.14659

A Nurse-Led Bridging Program to Reduce 30-Day Readmissions of Older Patients Discharged From Acute Care Units.

Gilbert T, Occelli P, Rabilloud M, Poupon-Bourdy S, Riche B, Touzet S, Bonnefoy M; PROUST Study Group.

A Nurse-Led Bridging Program to Reduce 30-Day Readmissions of Older Patients Discharged From Acute Care Units.

J Am Med Dir Assoc. 2021 Jun;22(6):1292-1299.e5. doi: 10.1016/j.jamda.2020.09.015. Epub 2020 Nov 20.

PMID: 33229305 Clinical Trial.

Objectives : Older hospitalized patients are at high risk of early readmissions, requiring the implementation of enhanced coordinated transition programs on discharge. The objective of this study was to evaluate the impact of a nurse-led transition bridging program on the rate of unscheduled readmissions of older patients within 30 days from discharge from geriatric acute care units.

Design : A stepped-wedge cluster randomized trial.

Setting and participants : Seven hundred five patients aged ≥75 years hospitalized in one of 10 acute geriatric units, with at least 2 readmission risk-screening criteria (derived from the Triage Risk Screening Tool), were included from July 2015 to August 2016.

https://pubmed.ncbi.nlm.nih.gov/33229305/

Association of Attention-Deficit/Hyperactivity Disorder in Childhood and Adolescence With the Risk of Subsequent Psychotic Disorder: A Systematic Review and Meta-analysis.

Nourredine M, Gering A, Fourneret P, Rolland B, Falissard B, Cucherat M, Geoffray MM, Jurek L.

Association of Attention-Deficit/Hyperactivity Disorder in Childhood and Adolescence With the Risk of Subsequent Psychotic Disorder: A Systematic Review and Meta-analysis.

Importance : Growing evidence supports an association between attention-deficit/hyperactivity disorder (ADHD) in childhood and subsequent psychotic disorders. Both disorders share physiopathological features such as attention deficits, dopaminergic imbalance, and genetic susceptibility. However, the results of epidemiologic studies have been conflicting.

Objective : To provide a quantitative synthesis of studies exploring the association between ADHD and the risk of subsequent psychotic disorder.

https://pubmed.ncbi.nlm.nih.gov/33625499/