La recherche au service de la performance en Santé
U.INSERM 1290 - La recherche au service de la performance en Santé
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Université Claude Bernard Lyon 1
U.INSERM 1290 - La recherche au service de la performance en Santé

TEOS: A framework for constructing operational definitions of medication adherence based on Timelines-Events-Objectives-Sources.

Dima AL, Allemann SS, Dunbar-Jacob J, Hughes DA, Vrijens B, Wilson IB.

TEOS: A framework for constructing operational definitions of medication adherence based on Timelines-Events-Objectives-Sources.

Br J Clin Pharmacol. 2021 Jun;87(6):2521-2533. doi: 10.1111/bcp.14659. Epub 2020 Dec 30.

PMID: 33220097

Aims :                                                                                                                                                                                                                                                                            Managing adherence to medications is a priority for health systems worldwide. Adherence research is accumulating, yet the quality of the evidence is reduced by various methodological limitations. In particular, the heterogeneity and low accuracy of adherence measures have been highlighted in many literature reviews. Recent consensus-based guidelines advise on best practices in defining adherence (ABC) and reporting of empirical studies (EMERGE). While these guidelines highlight the importance of operational definitions in adherence measurement, such definitions are rarely included in study reports. To support researchers in their measurement decisions, we developed a structured approach to formulate operational definitions of adherence.

https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bcp.14659

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